Common Name(s):

Black Bone Disease, Black Urine Disease

Alternative Names & Classifications:

Endogenous Ochronosis (CLINICAL), Alkaptonuric Ochronosis (ICD-11), Alkaptonuria (MESH)

Description

This results in the buildup of homogentisic acid, which causes the urine to turn black when exposed to air. Over time, this acid deposits in connective tissues, leading to a specific type of arthritis and heart valve damage.