Elexacaftor, Tezacaftor, and Ivacaftor
Type: Ingredient
Definition
A triad of pharmaceutical agents that modulate and potentiate the CFTR protein.
Botanical & Usage Details
Elexacaftor and tezacaftor are correctors that facilitate the cellular processing and trafficking of the CFTR protein to the cell surface. Ivacaftor is a potentiator that increases the open probability of the CFTR channel.