Definition

An extreme, abnormal skin reaction to sunlight or ultraviolet light exposure.

Clinical Details

Ultraviolet radiation induces apoptosis in skin cells, releasing nuclear antigens that the hyperactive immune system aggressively targets. This autoimmune reaction causes severe sunburns, blister formations, and the exacerbation of systemic symptoms after minimal sun exposure. Patients must strictly avoid sunlight and diligently utilize high-grade ultraviolet protection.