Alternative Names & Classifications:
Hypercortisolism (CLINICAL)
Description
Cushing's syndrome develops when body tissues are continuously exposed to excessive cortisol, either from endogenous overproduction or prolonged corticosteroid medication use. When caused specifically by a pituitary tumor secreting ACTH, it is termed Cushing's disease. The condition triggers profound changes in fat distribution, metabolism, and immune function, primarily affecting adults aged 20 to 50.