Alternative Names & Classifications:
Stargardt Disease (CLINICAL)
Description
Stargardt Disease is an autosomal recessive genetic disorder caused by a mutation in the ABCA4 gene, leading to the toxic buildup of a fatty byproduct called lipofuscin in the macula. As this toxic waste accumulates, it destroys the light-sensitive photoreceptors in the central retina. Unlike age-related macular degeneration, the progressive loss of central vision typically begins in childhood or early adulthood.