Alternative Names & Classifications:
Spinocerebellar Ataxia (CLINICAL)
Description
Spinocerebellar Ataxia (SCA) encompasses numerous distinct genetic mutations that lead to the slow, progressive degeneration of the cerebellum and, frequently, the spinal cord. The defective genes produce abnormal proteins that form toxic clumps inside neurons, leading to premature cell death. Depending on the specific genetic type, symptoms can emerge at any age, from early childhood to late adulthood.